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I have used most of the leading clotting agents; Quikclot, Quikclot ACS, Celox and Hemcon- not used Traumadex though. Of them all I would rate the Hemcon as the best option and worst price tag. The original Quikclot- the ACS version less so- produce an exothermic reaction at the wound site, potentially exacerbating the local tissue damage. The Celox and the original Quikclot are both powder forms which need to be poured into the wound- this creates issues for the patient when he reaches surgery, because of the additional wound debridement required- the Quikclot grains are quite small. I prefer the Hemcon because it is of a dressing form and produces no heat.
However it is not certain- from my experience- the level of bleeding that any of these will stop. A catastophic bleed may not allow enough time for clots to be formed, the clotting agents are to be considered additional measures and assistance and not the be all and end all. They can replace bandages, but only replace them and proper haemorraghe control should be followed first- torniquets etc if required. The other potential issue is whether the clots will survive the rapid introduction of additional fluids- IVs etc.
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